‘Fingerprinting’ studies on35S-labelled mammalian-cell ribosomal proteins
نویسندگان
چکیده
منابع مشابه
Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits
Our knowledge of the functions of metazoan ribosomal proteins in ribosome synthesis remains fragmentary. Using siRNAs, we show that knockdown of 31 of the 32 ribosomal proteins of the human 40S subunit (ribosomal protein of the small subunit [RPS]) strongly affects pre-ribosomal RNA (rRNA) processing, which often correlates with nucleolar chromatin disorganization. 16 RPSs are strictly required...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1971
ISSN: 0306-3283
DOI: 10.1042/bj1230035p